Match # 41. November 3, 2021, 14:00. Alushta. TCAPRNT "Krymskiy"
FC "Aluston-SCC" (Alushta) – FC "Sevastopol"
Referee – Oleg Lapishko (Simferopol)
Assistants referee: Sergey Zhabchenko (Simferopol) and Aleksandr Iurre (Sudak)
Reserve referee – Konstantin Popov (Simferopol)
Inspector – Oleg Kochergin (Alushta)
Match # 42. November 3, 2021, 14:00. Novopavlovka, Bakhchysaray district. SC "Skif"
FC "Rubin Yalta" – FC "Ocean" (Kerch)
Referee – Aleksandr Kreshchik (Saky)
Assistants referee: Refat Maskudov (Razdolnoe) and Maksim Strutskiy (Razdolnoe)
Reserve referee – Roman Shalverov (Pervomaiskoe)
Inspector – Oleg Fedorchenko (Yevpatoriya)
Match # 43. November 3, 2021, 15:00. Yevpatoriya. SC "Arena-Crimea"
FC "Yevpatoriya" – FC "Gvardeets" (Skvortsovo)
Referee – Dmitriy Ponomarenko (Dzhankoi)
Assistants referee: Shevket Dzhaparov (Simferopol) and Vitaliy Pasternak (Simferopol)
Reserve referee – Arsen Mamutov (Yevpatoriya)
Inspector – Andrey Priimak (Simferopol)
Match # 44. November 3, 2021, 15:30. Simferopol. STCNT of the CR
FC "TSK-Tavriya" (Simferopol) – FC "Kyzyltash" (Bakhchysaray)
Referee – Aleksey Polianin (Simferopol)
Assistants referee: Ekaterina Bibikova (Simferopol) and Denis Stetiukha (Sevastopol)
Reserve referee – Sergey Lysenko (Simferopol)
Inspector – Dmitriy Shalychev (Simferopol)