October 13, 2021, 15:00. Kerch. MSC n.a. the 50th anniversary of October
FC "Ocean" (Kerch) – FC "Kyzyltash" (Bakhchysaray)
Referee – Iurii Volkov (Simferopol)
Assistants referee: Vitaliy Karashchenko (Simferopol) and Aleksandr Iurre (Sudak)
Reserve referee – Denis Korablev (Kerch)
Inspector – Evgeniy Kolesnikov (Kerch)
October 13, 2021, 15:00. Sevastopol. SHC "Sevastopol"
FC "Sevastopol" – FC "Yevpatoriya"
Referee – Roman Dovbnia (Simferopol)
Assistants referee: Andrey Shershen (Simferopol) and Ernest Bekirov (Pervomaiskoe)
Reserve referee – Dmitriy Gachmin (Simferopol)
Inspector – Oleg Grebinchik (Bakhchysaray)
October 13, 2021, 15:00. Novopavlovka, Bakhchysaray district. SC "Skif"
FC "Rubin Yalta" – FC "Aluston-SCC" (Alushta)
Referee – Andrey Ganzheliuk (Kerch)
Assistants referee: Aleksandr Plakhotniuk (Yevpatoriya) and Arsen Mamutov (Yevpatoriya)
Reserve referee – Sergey Zhabchenko (Simferopol)
Inspector – Oleg Fedorchenko (Yevpatoriya)
October 13, 2021, 16:30. Agrarnoe, Simferopol city. Stadium "Krymteplitsa"
FC "TSK-Tavriya" (Simferopol) – FC "Gvardeets" (Skvortsovo)
Referee – Oleg Lapishko (Simferopol)
Assistants referee: Vitaliy Pasternak (Simferopol) and Shevket Dzhaparov (Simferopol)
Reserve referee – Aleksey Polianin (Simferopol)
Inspector – Sergey Ogar (Sevastopol)