Match # 25. October 2, 2021, 15:00. Yevpatoriya. SC "Arena-Crimea"
FC "Yevpatoriya" – FC "Sevastopol"
Referee – Oleg Lapishko (Simferopol)
Assistants referee: Dmitriy Domnikov (Simferopol) and Vitaliy Karashchenko (Simferopol)
Reserve referee – Aleksandr Kreshchik (Saky)
Inspector – Oleg Kochergin (Alushta)
Match # 26. October 2, 2021, 15:00. Novopavlovka, Bakhchysaray district. SC "Skif"
FC "Rubin Yalta" – FC "TSK-Tavriya" (Simferopol)
Referee – Denis Korablev (Kerch)
Assistants referee: Aleksey Grebinchik (Bakhchysaray) and Andrey Shershen (Simferopol)
Reserve referee – Sergey Lysenko (Simferopol)
Inspector – Andrey Priimak (Simferopol)
Match # 27. October 3, 2021, 15:00. Bakhchysaray. Stadium "Druzhba"
FC "Kyzyltash" (Bakhchysaray) – FC "Aluston-SCC" (Alushta)
Referee – Mikhail Verikovskii (Simferopol)
Assistants referee: Vitaliy Pasternak (Simferopol) and Dmitriy Gachmin (Simferopol)
Reserve referee – Denis Shudrik (Simferopol)
Inspector – Vitaliy Viktorov (Simferopol)
Match # 28. October 3, 2021, 15:30. Kerch. MSC n.a. the 50th anniversary of October
FC "Ocean" (Kerch) – FC "Gvardeets" (Skvortsovo)
Referee – Iurii Volkov (Simferopol)
Assistants referee: Arsen Mamutov (Yevpatoriya) and Aleksandr Plakhotniuk (Yevpatoriya)
Reserve referee – Andrey Ganzheliuk (Kerch)
Inspector – Anatoliy Oleinik (Simferopol)