Match # 23. September 26, 2021, 15:00. Bakhchysaray. Stadium "Druzhba"
FC "Kyzyltash" (Bakhchysaray) – FC "Rubin Yalta"
Referee – Nikita Sugak (Sevastopol)
Assistants referee: Aleksandr Iurre (Sudak) and Dmitriy Karmanov (Frunze, Saky district)
Reserve referee – Roman Shalverov (Pervomaiskoe)
Inspector – Iurii Abramenko (Simferopol)
Match # 21. September 26, 2021, 16:00. Sevastopol. SHC "Sevastopol"
FC "Sevastopol" – FC "Ocean" (Kerch)
Referee – Roman Dovbnia (Simferopol)
Assistants referee: Shevket Dzhaparov (Simferopol) and Ekaterina Bibikova (Simferopol)
Reserve referee – Evgeniy Kiva (Sevastopol)
Inspector – Vladimir Sirenko (Yalta)
Match # 22. September 26, 2021, 16:00. Novopavlovka, Bakhchysaray district. SC "Skif"
FC "Gvardeets" (Skvortsovo) – FC "Aluston-SCC" (Alushta)
Referee – Maksim Klim (Sevastopol)
Assistants referee: Oleg Mironov (Simferopol) and Denis Stetiukha (Sevastopol)
Reserve referee – Mikhail Verikovskii (Simferopol)
Inspector – Oleg Grebinchik (Bakhchysaray)
Match # 24. September 26, 2021, 16:00. Simferopol. STCNT of the CR
FC "TSK-Tavriya" (Simferopol) – FC "Yevpatoriya"
Referee – Aleksandr Kreshchik (Saky)
Assistants referee: Dmitriy Domnikov (Simferopol) and Ernest Bekirov (Pervomaiskoe)
Reserve referee – Iurii Volkov (Simferopol)
Inspector – Aleksandr Boitsan (Simferopol)